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Cheap flights from Santiago to Cusco from $192

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to Cusco departing on 16/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Santiago to Cusco

Cheap return flights

Logo
14:35 - 20:20SCL-CUZ
7h 45m1 stop
Logo
14:57 - 05:01CUZ-SCL
12h 04m1 stop
$368
Find Deal
Wed, 10 Sep - Thu, 11 Sep
Sky Airline Logo
23:05 - 06:45SCL-CUZ
9h 40m1 stop
Sky Airline Logo
11:40 - 22:15CUZ-SCL
8h 35m1 stop
$369Sky Airline
Find Deal
Sat, 1 Nov - Tue, 11 Nov
Sky Airline Logo
12:30 - 20:00SCL-CUZ
9h 30m1 stop
Sky Airline Logo
20:45 - 12:15CUZ-SCL
13h 30m2 stops
$372Sky Airline
Find Deal
Thu, 30 Oct - Thu, 13 Nov
LATAM Airlines Logo
17:55 - 00:35SCL-CUZ
8h 40m1 stop
LATAM Airlines Logo
09:30 - 14:50CUZ-SCL
3h 20mdirect
$374LATAM Airlines
Find Deal
Wed, 10 Sep - Thu, 11 Sep
Logo
01:35 - 19:55SCL-CUZ
20h 20m2 stops
Logo
14:57 - 05:01CUZ-SCL
12h 04m1 stop
$375
Find Deal
Tue, 9 Sep - Thu, 11 Sep
Sky Airline Logo
01:35 - 16:05SCL-CUZ
16h 30m2 stops
Sky Airline Logo
17:55 - 12:15CUZ-SCL
16h 20m2 stops
$386Sky Airline
Find Deal
Fri, 31 Oct - Tue, 11 Nov
Sky Airline Logo
01:35 - 19:55SCL-CUZ
20h 20m2 stops
Sky Airline Logo
07:25 - 22:10CUZ-SCL
12h 45m1 stop
$391Sky Airline
Find Deal
Fri, 10 Oct - Wed, 22 Oct
Sky Airline Logo
00:35 - 16:25SCL-CUZ
16h 50m2 stops
Sky Airline Logo
20:40 - 11:20CUZ-SCL
13h 40m2 stops
$392Sky Airline
Find Deal
Tue, 26 Aug - Wed, 3 Sep
Sky Airline Logo
01:35 - 19:55SCL-CUZ
20h 20m2 stops
Sky Airline Logo
20:40 - 12:00CUZ-SCL
13h 20m2 stops
$394Sky Airline
Find Deal
Fri, 10 Oct - Wed, 22 Oct
LATAM Airlines Logo
22:15 - 06:15SCL-CUZ
10h 00m1 stop
LATAM Airlines Logo
00:05 - 15:30CUZ-SCL
13h 25m1 stop
$459LATAM Airlines
Find Deal
Thu, 30 Oct - Wed, 12 Nov

Sky Airline flights from Santiago to Cusco

Our best Sky Airline deals on Santiago to Cusco flight tickets
Sky Airline
1 Nov
SCL23:05Santiago Arturo Merino Benitez
9h 40m
1 stop
CUZ06:45Cusco Velazco Astete
11 Nov
CUZ11:40Cusco Velazco Astete
8h 35m
1 stop
SCL22:15Santiago Arturo Merino Benitez
$369
Find similar
Sky Airline
30 Oct
SCL12:30Santiago Arturo Merino Benitez
9h 30m
1 stop
CUZ20:00Cusco Velazco Astete
13 Nov
CUZ20:45Cusco Velazco Astete
13h 30m
2 stops
SCL12:15Santiago Arturo Merino Benitez
$372
Find similar
Sky Airline
31 Oct
SCL01:35Santiago Arturo Merino Benitez
16h 30m
2 stops
CUZ16:05Cusco Velazco Astete
11 Nov
CUZ17:55Cusco Velazco Astete
16h 20m
2 stops
SCL12:15Santiago Arturo Merino Benitez
$386
Find similar

LATAM Airlines flights from Santiago to Cusco

Our best LATAM Airlines deals on Santiago to Cusco flight tickets
LATAM Airlines
10 Sept
SCL17:55Santiago Arturo Merino Benitez
8h 40m
1 stop
CUZ00:35Cusco Velazco Astete
11 Sept
CUZ09:30Cusco Velazco Astete
3h 20m
SCL14:50Santiago Arturo Merino Benitez
$374
Find similar
LATAM Airlines
30 Oct
SCL22:15Santiago Arturo Merino Benitez
10h 00m
1 stop
CUZ06:15Cusco Velazco Astete
12 Nov
CUZ00:05Cusco Velazco Astete
13h 25m
1 stop
SCL15:30Santiago Arturo Merino Benitez
$459
Find similar

momondo Fare Finder

 
Customise your flight search to find flights from Santiago to Cusco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 78,305 searches. Data last updated 2 August 2025.
Use the filters below to find and compare flights from Santiago to Cusco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Wed 10/9

14:35-20:20

1 stop7h 45m

Cusco Velazco Astete

Thu 11/9

14:57-05:01

1 stop12h 04m

$368

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Sat 1/11

23:05-06:45

1 stop9h 40m

Cusco Velazco Astete

Tue 11/11

11:40-22:15

1 stop8h 35m

$369

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Thu 30/10

12:30-20:00

1 stop9h 30m

Cusco Velazco Astete

Thu 13/11

20:45-12:15

2 stops13h 30m

$372

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Wed 10/9

17:55-00:35

1 stop8h 40m

Cusco Velazco Astete

Thu 11/9

09:30-14:50

Nonstop3h 20m

$374

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Tue 9/9

01:35-19:55

2 stops20h 20m

Cusco Velazco Astete

Thu 11/9

14:57-05:01

1 stop12h 04m

$375

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Fri 31/10

01:35-16:05

2 stops16h 30m

Cusco Velazco Astete

Tue 11/11

17:55-12:15

2 stops16h 20m

$386

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Fri 10/10

01:35-19:55

2 stops20h 20m

Cusco Velazco Astete

Wed 22/10

07:25-22:10

1 stop12h 45m

$391

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Tue 26/8

00:35-16:25

2 stops16h 50m

Cusco Velazco Astete

Wed 3/9

20:40-11:20

2 stops13h 40m

$392

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Fri 10/10

01:35-19:55

2 stops20h 20m

Cusco Velazco Astete

Wed 22/10

20:40-12:00

2 stops13h 20m

$394

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Thu 30/10

22:15-06:15

1 stop10h 00m

Cusco Velazco Astete

Wed 12/11

00:05-15:30

1 stop13h 25m

$459

Flights are sorted by cheapest return flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Cusco from

How to get the cheapest flight ticket from Santiago to Cusco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santiago and Cusco?

What is the cheapest month to fly to Cusco?

In general, November is the cheapest month to fly from Santiago to Cusco. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $375. If you aren’t able to travel during the month of November, then book flights to Cusco from Santiago during March instead. Flights to Cusco in March, while not as cheap as those in November, still average around $385.

What is the cheapest day to depart on your flight to Cusco?

The cheapest day to depart on your flight to Cusco is on a Monday when prices can be found for as low as $397. This is often the case because there is less demand to fly during this day of the week. The most expensive day to fly to Cusco is Wednesday, with ticket prices averaging around $757.

What is the cheapest time of day to depart on your flight to Cusco?

Our most recent data shows that the best time of day to fly to Cusco is in the afternoon. Flights from Santiago to Cusco during this time can be as low as $458. Flights to Cusco are more costly at midday, with an average ticket price of $738. Departure times at midday fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Santiago Arturo Merino Benitez to Cusco Velazco Astete flight route?

Fly from Santiago Arturo Merino Benitez to Cusco Velazco Astete for the best Santiago Arturo Merino Benitez - Cusco Velazco Astete flight prices

How far in advance should I book a flight to Cusco?

You are more likely to see cheaper flights to Cusco from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to Cusco for around $431 when searching weeks before you fly. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Cusco from Santiago for as low as $383 on momondo.

What cabin class options are available on Santiago Arturo Merino Benitez to Cusco Velazco Astete flights?

There are 2 cabin classes available to choose from on Santiago Arturo Merino Benitez to Cusco Velazco Astete flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Santiago to Cusco flights?

No. A direct flight is the cheapest option for a flight between Santiago to Cusco.

How have Santiago to Cusco flight prices changed over time?

As of August 2025, prices for Santiago to Cusco flights are approximately 5% more expensive when compared to flights at the same time last year.

When to book flights from Santiago to Cusco

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to Cusco according to our flight data. Find out which month and days have the cheapest flights.
Estimated return price

Cheap Santiago to Cusco (SCL to CUZ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to Cusco

Best price found

$192

Fastest flight time

3h 30m

Direct flights

Tue, Thu and Fri

Airports in Cusco

1 airport
The best one-way flight to Cusco from Santiago in the past 72 hours is $192. The best return flight deal from Santiago to Cusco found on momondo in the last 72 hours is $368.
The fastest flight from Santiago to Cusco takes 3h 30m
Direct flights go from Santiago to Cusco on Tuesday, Thursday and Friday. Airline offering direct flights is LATAM Airlines..
There is 1 airport near Cusco: Cusco Velazco Astete (CUZ)
Search flight deals

  • How far is Santiago Arturo Merino Benitez to Cusco Velazco Astete by plane?

    Santiago Arturo Merino Benitez and Cusco Velazco Astete are 2216.9 km apart from one another. A reasonable flight in good conditions will take 7h 45m.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Cusco Velazco Astete Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Cusco Velazco Astete Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to Cusco Velazco Astete Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Cusco Velazco Astete Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Santiago Arturo Merino Benitez Airport to Cusco Velazco Astete Airport.

  • What documentation or ID do you need to fly to Cusco Velazco Astete Airport?

    The travel and health documents you'll need for your trip to Cusco Velazco Astete Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's licence and a passport that is valid for six months after your intended arrival at Cusco Velazco Astete Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Santiago to Cusco?

  • What is the most popular airline from Santiago to Cusco?

Best airlines flying from Santiago to Cusco

Compare and see reviews for airlines that fly from Santiago to Cusco with momondo
Airline
Rating
Free cancellation
Price
LATAM AirlinesPriceFrom $394Free cancellationRating
7.5
1,823 reviews
Search LATAM Airlines flights

  • LATAM Airlines Flights From Santiago to Cusco

    LATAM Airlines is one of the most popular airlines flying from Santiago to Cusco, operating 4 flights/week on average for this route. A good LATAM Airlines flight deal for Santiago to Cusco starts from $255 round-trip, up to an average price of $298. Our users have rated LATAM Airlines at 7.5/10.

Travelling to a place near Cusco?

Book flights to Cusco if you plan to visit one of these locations
Machu Picchu

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to Cusco?

It is quick and easy to find Santiago to Cusco flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Cusco that suits you.

Can I find flights from Santiago to Cusco with flexible booking policies on momondo?

All flight searches from Santiago to Cusco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santiago to Cusco?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Santiago to Cusco.

I’m not ready to book a flight from Santiago to Cusco right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Santiago to Cusco flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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