Cheap flights from Santiago to Cusco from $183

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to Cusco departing on 5/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult

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JetSMART Logo
11:24 - 16:31SCL-CUZ
7h 07m1 stop
JetSMART Logo
22:22 - 05:01CUZ-SCL
28h 39m1 stop
$346JetSMART
Find Deal
Thu, 26 Mar - Wed, 1 Apr
JetSMART Logo
04:51 - 11:09SCL-CUZ
7h 18m1 stop
JetSMART Logo
17:17 - 04:01CUZ-SCL
9h 44m1 stop
$349JetSMART
Find Deal
Sat, 2 May - Fri, 8 May
JetSMART Logo
04:51 - 15:54SCL-CUZ
12h 03m1 stop
JetSMART Logo
15:47 - 04:01CUZ-SCL
11h 14m1 stop
$351JetSMART
Find Deal
Wed, 8 Apr - Tue, 14 Apr
JetSMART Logo
11:24 - 16:31SCL-CUZ
7h 07m1 stop
JetSMART Logo
21:02 - 10:39CUZ-SCL
11h 37m1 stop
$358JetSMART
Find Deal
Sat, 21 Mar - Fri, 27 Mar
Sky Airline Logo
20:15 - 06:25SCL-CUZ
11h 10m1 stop
Sky Airline Logo
18:30 - 05:50CUZ-SCL
10h 20m1 stop
$360Sky Airline
Find Deal
Sun, 5 Apr - Wed, 8 Apr
JetSMART Logo
04:51 - 15:54SCL-CUZ
12h 03m1 stop
JetSMART Logo
16:27 - 04:01CUZ-SCL
10h 34m1 stop
$369JetSMART
Find Deal
Wed, 8 Apr - Wed, 15 Apr
JetSMART Logo
11:24 - 20:26SCL-CUZ
11h 02m1 stop
JetSMART Logo
06:57 - 05:01CUZ-SCL
20h 04m1 stop
$371JetSMART
Find Deal
Fri, 27 Mar - Sat, 4 Apr
Sky Airline Logo
11:30 - 20:50SCL-CUZ
10h 20m1 stop
Sky Airline Logo
12:05 - 11:15CUZ-SCL
22h 10m2 stops
$372Sky Airline
Find Deal
Sun, 5 Apr - Wed, 8 Apr
JetSMART Logo
11:24 - 20:26SCL-CUZ
11h 02m1 stop
JetSMART Logo
21:47 - 10:39CUZ-SCL
10h 52m1 stop
$381JetSMART
Find Deal
Fri, 20 Mar - Sat, 28 Mar
JetSMART Logo
05:51 - 21:24SCL-CUZ
17h 33m1 stop
JetSMART Logo
16:42 - 04:01CUZ-SCL
10h 19m1 stop
$384JetSMART
Find Deal
Thu, 2 Apr - Thu, 9 Apr

JetSMART flights from Santiago to Cusco

Our best JetSMART deals on Santiago to Cusco flight tickets
JetSMART
26 Mar
SCL11:24Santiago Arturo Merino Benitez
7h 07m
1 stop
CUZ16:31Cusco Velazco Astete
1 Apr
CUZ22:22Cusco Velazco Astete
28h 39m
1 stop
SCL05:01Santiago Arturo Merino Benitez
JetSMART
30 Apr
SCL04:51Santiago Arturo Merino Benitez
11h 28m
1 stop
CUZ15:19Cusco Velazco Astete
6 May
CUZ16:27Cusco Velazco Astete
10h 34m
1 stop
SCL04:01Santiago Arturo Merino Benitez
JetSMART
2 May
SCL04:51Santiago Arturo Merino Benitez
7h 18m
1 stop
CUZ11:09Cusco Velazco Astete
8 May
CUZ17:17Cusco Velazco Astete
9h 44m
1 stop
SCL04:01Santiago Arturo Merino Benitez

Sky Airline flights from Santiago to Cusco

Our best Sky Airline deals on Santiago to Cusco flight tickets
Sky Airline
5 Apr
SCL20:15Santiago Arturo Merino Benitez
11h 10m
1 stop
CUZ06:25Cusco Velazco Astete
8 Apr
CUZ18:30Cusco Velazco Astete
10h 20m
1 stop
SCL05:50Santiago Arturo Merino Benitez
Sky Airline
5 Apr
SCL11:30Santiago Arturo Merino Benitez
10h 20m
1 stop
CUZ20:50Cusco Velazco Astete
8 Apr
CUZ12:05Cusco Velazco Astete
22h 10m
2 stops
SCL11:15Santiago Arturo Merino Benitez
Sky Airline
4 Apr
SCL00:35Santiago Arturo Merino Benitez
16h 40m
2 stops
CUZ16:15Cusco Velazco Astete
8 Apr
CUZ21:20Cusco Velazco Astete
7h 30m
1 stop
SCL05:50Santiago Arturo Merino Benitez

momondo Fare Finder

 
Customise your flight search to find flights from Santiago to Cusco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 78,305 searches. Data last updated 27 November 2025.
Use the filters below to find and compare flights from Santiago to Cusco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Thu 26/3

11:24-16:31

1 stop7h 07m

Cusco Velazco Astete

Wed 1/4

22:22-05:01

1 stop28h 39m

$346

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Sat 2/5

04:51-11:09

1 stop7h 18m

Cusco Velazco Astete

Fri 8/5

17:17-04:01

1 stop9h 44m

$349

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Wed 8/4

04:51-15:54

1 stop12h 03m

Cusco Velazco Astete

Tue 14/4

15:47-04:01

1 stop11h 14m

$351

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Sat 21/3

11:24-16:31

1 stop7h 07m

Cusco Velazco Astete

Fri 27/3

21:02-10:39

1 stop11h 37m

$358

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Sun 5/4

20:15-06:25

1 stop11h 10m

Cusco Velazco Astete

Wed 8/4

18:30-05:50

1 stop10h 20m

$360

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Wed 8/4

04:51-15:54

1 stop12h 03m

Cusco Velazco Astete

Wed 15/4

16:27-04:01

1 stop10h 34m

$369

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Fri 27/3

11:24-20:26

1 stop11h 02m

Cusco Velazco Astete

Sat 4/4

06:57-05:01

1 stop20h 04m

$371

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Sun 5/4

11:30-20:50

1 stop10h 20m

Cusco Velazco Astete

Wed 8/4

12:05-11:15

2 stops22h 10m

$372

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Fri 20/3

11:24-20:26

1 stop11h 02m

Cusco Velazco Astete

Sat 28/3

21:47-10:39

1 stop10h 52m

$381

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Thu 2/4

05:51-21:24

1 stop17h 33m

Cusco Velazco Astete

Thu 9/4

16:42-04:01

1 stop10h 19m

$384

Flights are sorted by cheapest return flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Cusco from

How to get the cheapest flight ticket from Santiago to Cusco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Cusco?

In general, March is the cheapest month to fly from Santiago to Cusco. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $386. If you aren’t able to travel during the month of March, then book flights to Cusco from Santiago during November instead. Flights to Cusco in November, while not as cheap as those in March, still average around $400.

What is the cheapest day to depart on your flight to Cusco?

The cheapest day to depart on your flight to Cusco is on a Monday when prices can be found for as low as $427. This is often the case because there is less demand to fly during this day of the week. The most expensive day to fly to Cusco is Wednesday, with ticket prices averaging around $853.

What is the cheapest time of day to depart on your flight to Cusco?

Our most recent data shows that the best time of day to fly to Cusco is in the afternoon. Flights from Santiago to Cusco during this time can be as low as $484. Flights to Cusco are more costly at midday, with an average ticket price of $853. Departure times at midday fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Santiago Arturo Merino Benitez to Cusco Velazco Astete flight route?

Fly from Santiago Arturo Merino Benitez to Cusco Velazco Astete for the best Santiago Arturo Merino Benitez - Cusco Velazco Astete flight prices

How far in advance should I book a flight to Cusco?

You are more likely to see cheaper flights to Cusco from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to Cusco for around $430 when searching weeks before you fly. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Cusco from Santiago for as low as $355 on momondo.

What cabin class options are available on Santiago Arturo Merino Benitez to Cusco Velazco Astete flights?

There are 2 cabin classes available to choose from on Santiago Arturo Merino Benitez to Cusco Velazco Astete flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Santiago to Cusco flights?

No. A direct flight is the cheapest option for a flight between Santiago to Cusco.

How have Santiago to Cusco flight prices changed over time?

As of November 2025, prices for Santiago to Cusco flights are approximately 12% more expensive when compared to flights at the same time last year.

When to book flights from Santiago to Cusco

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to Cusco according to our flight data. Find out which month and days have the cheapest flights.
Estimated return price

Cheap Santiago to Cusco (SCL to CUZ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to Cusco

Fastest flight time

3h 30m

Direct flights

Mon

Airports in Cusco

1 airport
The fastest flight from Santiago to Cusco takes 3h 30m
Direct flights go from Santiago to Cusco on Monday. Airline offering direct flights is LATAM Airlines..
There is 1 airport near Cusco: Cusco Velazco Astete (CUZ)
  • How far is Santiago Arturo Merino Benitez to Cusco Velazco Astete by plane?

    Santiago Arturo Merino Benitez and Cusco Velazco Astete are 2216.9 km apart from one another. A reasonable flight in good conditions will take 7h 07m.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Cusco Velazco Astete Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Cusco Velazco Astete Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to Cusco Velazco Astete Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Cusco Velazco Astete Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Santiago Arturo Merino Benitez Airport to Cusco Velazco Astete Airport.

  • What documentation or ID do you need to fly to Cusco Velazco Astete Airport?

    The travel and health documents you'll need for your trip to Cusco Velazco Astete Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's licence and a passport that is valid for six months after your intended arrival at Cusco Velazco Astete Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Santiago to Cusco?

  • What is the most popular airline from Santiago to Cusco?

Best airlines flying from Santiago to Cusco

Compare and see reviews for airlines that fly from Santiago to Cusco with momondo
Airline
Rating
Free cancellation
Price
LATAM AirlinesPriceFrom $392Free cancellationRating
7.5
1,886 reviews
Search LATAM Airlines flights
  • LATAM Airlines Flights From Santiago to Cusco

    LATAM Airlines is one of the most popular airlines flying from Santiago to Cusco, operating 10 flights/week on average for this route. A good LATAM Airlines flight deal for Santiago to Cusco starts from $392 round-trip, up to an average price of $504. Our users have rated LATAM Airlines at 7.5/10.

Travelling to a place near Cusco?

Book flights to Cusco if you plan to visit one of these locations
Machu Picchu

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to Cusco?

It is quick and easy to find Santiago to Cusco flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Cusco that suits you.

Can I find flights from Santiago to Cusco with flexible booking policies on momondo?

All flight searches from Santiago to Cusco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santiago to Cusco?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Santiago to Cusco.

I’m not ready to book a flight from Santiago to Cusco right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Santiago to Cusco flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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1 adult
Sat 27/12
Sat 3/1

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