Cheap flights from Sao Paulo to Santiago from $152

The month of November is, on average, the cheapest month to fly to Santiago from Sao Paulo, with most prices found around $354. The month of March is another great option to travel to Santiago, with average flight prices from Sao Paulo averaging around $354.

The cheapest day to depart from Sao Paulo to Santiago is on a Monday. Travellers who choose to depart for Santiago on a Monday will often find tickets for as low as $2,479. If your travel schedule is flexible, try to avoid departing on a Friday because tickets tend to average around $2,671. These prices are subject to change though, so be sure to set up a Price Alert for flights to Santiago.

Flying to Santiago from Sao Paulo in the evening is the least expensive time of day to depart. momondo users have found prices as low as $2,547 when looking at flights departing in the evening. Flights in the afternoon are often more expensive, with an average ticket price of $2,632.

Fly from Sao Paulo Guarulhos Intl to Santiago Arturo Merino Benitez for the best Sao Paulo - Santiago Arturo Merino Benitez flight prices

You are more likely to see cheaper flights to Santiago from Sao Paulo when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $397 when searching weeks before you fly. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Sao Paulo for as low as $368 on momondo.

There are 3 cabin classes available to choose from on Sao Paulo to Santiago flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Historically, on average around 23% of flights between Sao Paulo and Santiago have experienced a delay on any given week. The average delay length over the past 12 months has been 124 minutes.

Generally, flights departing in the morning tend to experience fewer delays. Flights departing at night have, in the past, seen delays more frequently in comparison.

Thursday is statistically the day of the week that experiences the fewest delays on this flight route. Friday has historically seen more delays on average compared to the rest of the week.

According to our data, LATAM Airlines have had the fewest delays on this route over the last 12 months, with about 22% of their flights experiencing any sort of delay.

30 flights are operational daily from Sao Paulo to Santiago as of July 2026. The most popular departure time for this route is 14:00, with 43% of flights per day taking off in the afternoon.

The number of flights available between Sao Paulo and Santiago is 216 per week as of July 2026. The most frequent departure day is Fri, with 18% of weekly flights leaving on this day.