Behind every great day is a great night at the Comfort Inn and Suites at I-85 hotel in Spartanburg, SC. Our smoke-free hotel is near attractions like the University of South Carolina, Hollywild Animal Park, Chapman Cultural Center and the Hatcher Garden and Woodland Preserve. Take advantage of our free hot breakfast, free WiFi, fitness center and guest laundry facilities. Guest rooms include refrigerators, microwaves, coffee makers and hair dryers. Upper-tier suites have even more amenities, such as a hot tubs. We also offer membership to the Choice Privileges Program, which gives members the opportunity to earn valuable rewards points toward airline miles, gift cards and free hotel room nights.