Discover northwestern Illinois from the comfort of this quaint Galesburg hotel, just minutes from Knox College and Seminary Street. Conveniently located off the I-74, the Best Western Prairie Inn & Conference Center is just three miles from the heart of Galesburg, IL. Guests are just minutes from historic Seminary Street, offering shopping, dining and more. History and culture lovers delight in Galesburg's many well-known attractions, from the Orpheum Theatre to the Galesburg Railroad Museum to the birthplace of famed writer Carl Sandburg. A scenic self-guided car tour takes guests from this Galesburg hotel to many of these popular attractions. The hotel is a great choice for families visiting students at Knox College or Carl Sandburg College, both just minutes away. It's also a convenient spot for experiencing seasonal events, like Railroad Days and the Stearman Fly-In. This Illinois hotel also offers easy access for corporate travelers doing business at RFMS, BNSF and Masters Educational Services. A full-service Galesburg hotel with the only full-service event location in the area, we offer the highest quality amenities. Our ballroom can seat up to 300 guests, making the property a perfect choice for your next meeting, banquet, reunion or wedding. All rooms at the Best Western Prairie Inn & Conference Center include a 50-inch LED Smart TV and have cable satellite & HBO®. All rooms come with a microwave and refrigerator. Select rooms offer a private patio entrance to our beautiful courtyard. Other amenities available at this Galesburg hotel include an indoor pool, exercise facility, room service and free Wi-Fi access. Make the Best Western Prairie Inn & Conference Center your home away from home during your next visit to Galesburg, IL. Contact our friendly staff to reserve your stay! Enjoy your stay. Visit our beautiful courtyard, complete with gazebo, games and putting green!